PBB and PBDE Congener Analysis

PBB and PBDE Congener Analysis
Specialty Analytical uses a Thermo Scientific TSQ Quantum XLS Triple Quadrupole GC/MS/MS to analyze water, soil and tissue samples for PBB and PBDE congeners by EPA Method 1614 "Brominated Diphenyl Ethers in Water Soil, Sediment and Tissue by HRGC/HRMS". This technology achieves detection limits in the ppq (parts per quadrillion) range for water samples and ppt (parts per trillion) for soils and tissues. The resolution and selectivity of the tandem Mass Spectrometers allows for unambiguous quantitation of the PBB and PBDE congeners.
Specialty Analytical is pioneering the use of this instrumentation for analysis of commercial environmental samples.
Trace Mercury Analysis
Polybrominated Biphenyls (PBBs) and Polybrominated Diphenyl Ethers (PBDEs) have been used since the 1960s. They are synthetic compounds used as additives to retard fire and flames in a variety of commercial and household products. The relatively weak carbon-bromine bond is thermally-labile. The thermal energy releases bromine radicals that intercept carbon radicals to decrease flame, while simultaneously reducing heat and carbon monoxide production.
Commercial PBBs and PBDEs are manufactured by bromination of biphenyl and diphenyl ethers resulting in a mixture of biphenyls and diphenyl ethers containing tetra-, penta-, hepta-, octa-, and deca-congeners in various percentages. PBBs and PBDEs are structurally similar to polychlorinated biphenyls (PCBs).
There are 209 theoretically possible congeners divided into 10 congener groups from mono- to deca-PBB or PBDE. They are numbered according to the system originally designed for PCBs by the International Union of Pure and Applied Chemistry (IUPAC).
The use of these congeners in flame retardants has increased the prevalence of these compounds in everyday living. They can be found in furniture, in dust particles in the air, and in human breast milk. Studies have shown one of the most widely used congeners, Penta-BDE, can lead to alterations in neurodevelopment in prenatal mice.
Recent research studies have indicated that these PBDE and PBB compounds are persistent and bioaccumulating in the environment. Such compounds have been linked to adverse health effects that pose a potential risk to both animals and the human population.