PCB Congener Analysis

PCB Congener Analysis
Specialty Analytical uses a Thermo Scientific TSQ Quantum XLS Triple Quadrupole GC/MS/MS to analyze water, soil, sediment and tissue samples for the full list of 209 Congeners by EPA Method 1668 "Chlorinated Biphenyl Congeners in Water, Soil, Sediment, Biosolids, and Tissue by HRGC/HRMS". This technology achieves detection limits in the ppq (parts per quadrillion) range for water samples and ppt (parts per trillion) for soils and tissues. The resolution and selectivity of the tandem Mass Spectrometers allows for unambiguous quantitation of all 209 PCB Congeners.
Specialty Analytical is pioneering the use of this instrumentation for analysis of commercial environmental samples.
Trace Mercury Analysis
PCB Congener is a generic term for a family of 209 chlorinated isomers of biphenyl. The biphenyl molecule is composed of two six-sided carbon rings connected at one carbon site on each ring. Ten sites remain for chlorine atoms to join the biphenyl molecule. The term polychlorinated biphenyl (PCB) has been used to refer to the biphenyl molecule with one to ten chlorine substitutions, as shown in the above structure. In 1980, a numbering system was developed which assigned a sequential number to each of the 209 PCB congeners. See a listing of the 209 PCB Congeners
With few exceptions, PCBs were manufactured as a mixture of various PCB congeners through progressive chlorination of batches of biphenyl until a certain target percentage of chlorine by weight was achieved. Commercial mixtures with higher percentages of chlorine contained higher proportions of the more heavily chlorinated congeners, but all congeners could be expected to be present at some level in all mixtures. While PCBs were manufactured and sold under many names, the most common was the Aroclor series.
Aroclor is a PCB mixture produced from approximately 1930 until their production was banned in 1979. It is one of the most commonly known trade names for PCB mixtures. There are many types of Aroclors and each has a distinguishing suffix number that indicates the degree of chlorination. The numbering standard for the different Aroclors is as follows: The first two digits generally refer to the number of carbon atoms in the phenyl rings (for PCBs this is 12), the second two numbers indicate the percentage of chlorine by mass in the mixture. For example, the name Aroclor 1254 means that the mixture contains approximately 54% chlorine by weight.
PCBs cause cancer in animals and are probably carcinogenic in humans (group 2A classification, International Agency for Research on Cancer).Recent evidence suggests that PCBs might also have adverse reproductive, developmental, and endocrine effects.